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A brief review of genome editing technology for generating animal models

Haoyi WANG, Sen WU, Mario R. CAPECCHI, Rudolf JAENISCH

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 123-128 doi: 10.15302/J-FASE-2019309

Abstract:

The recent development of genome editing technologies has given researchers unprecedented power to alter DNA sequences at chosen genomic loci, thereby generating various genetically edited animal models. This mini-review briefly summarizes the development of major genome editing tools, focusing on the application of these tools to generate animal models in multiple species.

Keywords： animal model CRISPR genome editing TALEN ZFN

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The R&D of Flue Gas Pollutants Deep-Removal Technology for Coal-fired Power Plants

Xiao-lu Zhang

Frontiers of Engineering Management 2015, Volume 2, Issue 4, Pages 359-363 doi: 10.15302/J-FEM-2015057

Abstract: The flue gas pollutants deep-removal technology (DRT) focusing on PM removal is the prime method of

Keywords： coal-fired power plant pollutants emission reduction PM_2.5 flue gas pollutants deep-removal

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Strengthening the R&D of Engineering Technology and Developing the Polyester Industry of China

Jiang Shicheng

Strategic Study of CAE 2001, Volume 3, Issue 3, Pages 27-33

Abstract:

Due to the technology development and market demand, the PET industry has been developed very quicklyThe stress is placed on the development and research of the domestic PET engineering technology and the

Keywords： polyester technology development market suggestion

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FULL TIME-SPACE GOVERNANCE STRATEGY AND TECHNOLOGY FOR CROPLAND NON-POINT POLLUTION CONTROL IN CHINA

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 4, Pages 593-606 doi: 10.15302/J-FASE-2023522

Abstract: The 4R chain technology system is specifically reviewed, including source reduction, process retentionThe 4R chain technology system with the full time-space governance strategy was applied at the scale

Keywords： 4R chain technology system agricultural non-point source pollution case study full time-space governance

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A NEW APPROACH TO HOLISTIC NITROGEN MANAGEMENT IN CHINA

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 3, Pages 490-510 doi: 10.15302/J-FASE-2022453

Abstract:

● Progress on nitrogen management in agriculture is overviewed in China.

Keywords： 4R technology food chain N management N use efficiency soil-crop system sustainable management

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R&D of the ground-coupled heat pump technology in China

Nairen DIAO, Ping CUI, Junhong LIU, Zhaohong FANG,

Frontiers in Energy 2010, Volume 4, Issue 1, Pages 47-54 doi: 10.1007/s11708-009-0080-3

Abstract: In this paper, research on and development of the GCHP technology in China are summarized.

Keywords： ground source heat pump ground heat exchanger HVAC China

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Global Competitive Situation of 6G Key Technology R&D and China’s Countermeasures

Zhu Guangxu , Li Yang , Chen Yi , Chai Shuqi , Shi Qingjiang , Luo Zhiquan

Strategic Study of CAE 2023, Volume 25, Issue 6, Pages 9-17 doi: 10.15302/J-SSCAE-2023.06.002

Abstract: digital economy is characterized by mutual promotion and dependence, with significant value in key technologyprinciples and current development status of key 6G technologies from three dimensions: 6G wireless technology, network technology, and security technology.It evaluates China’s global competitiveness in these key technology directions, specifically includingwireless artificial intelligence (AI), massive MIMO technology, terahertz communication, intelligent

Keywords： 6G mobile communication digital economy wireless technology network technology security technology

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Design and R&D Progress of China Lead-Based Reactor for ADS Research Facility Review

Yican Wu

Engineering 2016, Volume 2, Issue 1, Pages 124-131 doi: 10.1016/J.ENG.2016.01.023

Abstract: The China Lead-based Reactor (CLEAR), proposed by the Institute of Nuclear Energy Safety Technology,was selected as the reference reactor for ADS development, as well as for the technology developmentIn order to validate and test the key components and integrated operating technology of the lead-based

Keywords： Accelerator-driven subcritical system (ADS) China Lead-based Reactor (CLEAR) Lead-bismuth eutectic (LBE) TechnologyR& D

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Experimental study on saturated flow boiling heat transfer of R290/R152a binary mixtures in a horizontal

Xin ZOU, Maoqiong GONG, Gaofei CHEN, Zhaohu SUN, Jianfeng WU

Frontiers in Energy 2010, Volume 4, Issue 4, Pages 527-534 doi: 10.1007/s11708-010-0109-7

Abstract: An experimental study on the saturated flow boiling heat transfer for a binary mixture of R290/R152aThe result shows that the total mean deviation is 10.41% for R290/R152a mixtures, with 97.6% of the predictions

Keywords： flow boiling heat transfer binary mixture R290/R152a

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Optimization of cellulase production using

Saravanan P, Muthuvelayudham R, Rajesh Kannan R, Viruthagiri T

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4, Pages 443-452 doi: 10.1007/s11705-012-1225-1

Abstract: The potential of for cellulase production using pineapple waste as substrate has been investigated. A maximum cellulase activity of 9.23 U/mL is obtained under the optimum experimental conditions: pH (5.5), temperature (37.5°C), initial substrate concentration (3%), inoculum concentration (6.6 × 10 ?CFU/mL), and culture time (6 days). Box-Behnken design (BBD) statistical tool and genetic algorithm (GA) are used to optimize the process parameters. The BBD study of linear and quadratic interactive effects of experimental variables on the desired response of cellulase activity showed that the second order polynomial is significant ( = 0.9414). The experimental cellulase activity under the optimal conditions identified by the BBD is 9.23 U/mL and that by GA is 6.98 U/mL. This result indicates that the BBD model gives better result than GA in the present case.

Keywords： cellulase pineapple waste Trichoderma reesei Box-Behnken design genetic algorithm

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Opinion: Agriculture Green Development

John R. PORTER

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 1, Pages 117-119 doi: 10.15302/J-FASE-2019315

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Design concepts of an aircraft wing: composite and morphing airfoil with auxetic structures

P R BUDARAPU,Sudhir Sastry Y B,R NATARAJAN

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 4, Pages 394-408 doi: 10.1007/s11709-016-0352-z

Abstract: This paper is categorized into two parts. (1) A frame work to design the aircraft wing structure and (2) analysis of a morphing airfoil with auxetic structure. The developed design frame work in the first part is used to arrive at the sizes of the various components of an aircraft wing structure. The strength based design is adopted, where the design loads are extracted from the aerodynamic loads. The aerodynamic loads acting on a wing structure are converted to equivalent distributed loads, which are further converted point loads to arrive at the shear forces, bending and twisting moments along the wing span. Based on the estimated shear forces, bending and twisting moments, the strength based design is employed to estimate the sizes of various sections of a composite wing structure. A three dimensional numerical model of the composite wing structure has been developed and analyzed for the extreme load conditions. Glass fiber reinforced plastic material is used in the numerical analysis. The estimated natural frequencies are observed to be in the acceptable limits. Furthermore, the discussed design principles in the first part are extended to the design of a morphing airfoil with auxetic structure. The advantages of the morphing airfoil with auxetic structure are (i) larger displacement with limited straining of the components and (ii) unique deformation characteristics, which produce a theoretical in-plane Poisson’s ratio of −1. Aluminum Alloy AL6061-T651 is considered in the design of all the structural elements. The compliance characteristics of the airfoil are investigated through a numerical model. The numerical results are observed to be in close agreement with the experimental results in the literature.

Keywords： wing design aerodynamic loads morphing airfoil auxetic structures negative Poisson’s ratio

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A photolysis coefficient for characterizing the response of aqueous constituents to photolysis

David R. HOKANSON,Ke LI,R. Rhodes TRUSSELL

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 3, Pages 428-437 doi: 10.1007/s11783-015-0780-3

Abstract: UV photolysis and UV based advanced oxidation processes (AOPs) are gaining more and more attention for drinking water treatment. Quantum yield ( ) and molar absorption coefficient ( ) are the two critical parameters measuring the effectiveness of photolysis of a compound. The product of the two was proposed as a fundamental measure of a constituent’s amenability to transformation by photolysis. It was shown that this product, named the photolysis coefficient, , can be determined using standard bench tests and captures the properties that govern a constituent’s transformation when exposed to light. The development showed the photolysis coefficient to be equally useful for microbiological, inorganic and organic constituents. Values of calculated by the authors based on quantum yield and molar absorption coefficient data from the literature were summarized. Photolysis coefficients among microorganisms ranged from 8500 to more than 600000 and are far higher than for inorganic and organic compounds, which varied over a range of approximately 10 to 1000 and are much less sensitive to UV photolysis than the microorganisms.

Keywords： UV photolysis disinfection advanced oxidation N-nitrosodimethylamine quantum yield absorption coefficient

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ZnO nanorefrigerant in R152a refrigeration system for energy conservation and green environment

SENDIL KUMAR,R. ELANSEZHIAN

Frontiers of Mechanical Engineering 2014, Volume 9, Issue 1, Pages 75-80 doi: 10.1007/s11465-014-0285-y

Abstract: on the basis of the concept of the nanofluids, which was prepared by mixing ZnO nanoparticles with R152aThe conventional refrigerant R134a has a global warming potential (GWP) of 1300 whereas R152a has a significantZnO nanoparticles with refrigerant mixture were used in HFC R152a refrigeration system.of nano ZnO ranges in the order of 0.1% v, 0.3% v and 0.5%v with particle size of 50 nm and 150 g of R152aThe usage of R152a with zero ozone depleting potential (ODP) and very less GWP and thus provides a green

Keywords： ZnO nanorefrigerant reduced GWP COP pressure ratio green energy